Why Diabetic Wounds Don't Heal
The Cellular Failure Behind Chronic Wounds
Malaysia has one of the highest diabetes rates in Southeast Asia — over 3.9 million Malaysians live with diabetes. Diabetic foot ulcers and chronic wounds represent one of the most challenging complications, driven by impaired cellular signalling, poor vascularisation, and chronic inflammation.
In diabetic tissue, cells lose their ability to receive and respond to healing signals. iPSC exosomes deliver a concentrated healing payload that bypasses this receptor dysfunction and directly activates the regenerative cascade.
- Activates keratinocyte and fibroblast proliferation
- Stimulates angiogenesis (new capillary growth) into wound bed
- Modulates chronic inflammation to allow healing
- Deposits extracellular matrix proteins for wound closure
- Reduces bacterial biofilm susceptibility
- Accelerates wound closure in clinical observations by 30–50%
